Cuspal VTs - Recognition and Management

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Raja Selvaraj

Professor of Cardiology, JIPMER

Anatomy

Outflow tracts relation

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Niloufar Tabatabaei and Samuel J. Asirvatham. Circulation: Arrhythmia and Electrophysiology. 2009;2:316–326

LVOT

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RVOT

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Liao .. Ouyang. Idiopathic Ventricular Arrhythmias Originating From the Pulmonary Sinus Cusp: Prevalence, Electrocardiographic/Electrophysiological Characteristics, and Catheter Ablation. JACC 2015;66:2633-2644

RVOT

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Vickram … Narasimhan. JOA 2020;36:471-477

ECG identification

Outflow tract

  • Limb leads to identify OT origin
  • Precordial leads to localize

V3 transition - RVOT or LVOT

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Ouyang … Kuck. JACC 2002;39:500-508

ECG Algorithms

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Anderson et al. Circ Arrhythmia 2019;12:e007392

PA-VA vs RVOT VA

  • Higher R wave in inferior leads
  • Higher aVL / aVR q wave ratio
  • Increased R/S in V2

Y. Sekiguchi, K. Aonuma, A. Takahashi, et al. Electrocardiographic and electrophysiologic characteristics of ventricular tachycardia originating within the pulmonary artery J Am Coll Cardiol, 45 (2005), pp. 887-895

Coupling interval variability

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Bradfield JS, Homsi M, Shivkumar K, Miller JM. Coupling interval variability differentiates ventricular ectopic complexes arising in the aortic sinus of valsalva and great cardiac vein from other sources: mechanistic and arrhythmic risk implications. J Am Coll Cardiol. 2014;63(20):2151-2158. 10.1016/j.jacc.2014.02.551

EP identification

Start with a deeply placed CS catheter

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Distinct EGM when mapping above the valve

  • Muscle sleeve with fibrous / fatty tissue acting as substrate
  • Typically seen above the aortic valve and pulmonary valve
  • Late in sinus rhythm and early before PVC

Komandoor S. Srivathsan et al. Mechanisms and Utility of Discrete Great Arterial Potentials in the Ablation of Outflow Tract Ventricular Arrhythmias. Circulation: Arrhythmia and Electrophysiology. 2008;1:30–38

Potential reversal in LCC

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Selvaraj et al. Heart 2011

Pre potential in Pulmonary cusp

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Vickram … Narasimhan. JOA 2020;36:471-477

Unipolar EGM

  • Concordant with bipolar for RVOT without prior ablation
  • May not concur in setting of prior ablation
  • May not be useful while mapping above the valve

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Conflict between pace mapping and activation mapping

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Wavefront spread

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Csaba Herczku … Josep Brugada. Mapping Data Predictors of a Left Ventricular Outflow Tract Origin of Idiopathic Ventricular Tachycardia With V3 Transition and Septal Earliest Activation. Circulation: Arrhythmia and Electrophysiology. 2012;5:484–491

Ablation

Power

  • 15-30 W may suffice
  • Immediate cessation of PVCs indicator of success

Kabilan … Raja Selvaraj. Low power ablation for left coronary cusp ventricular tachycardia—Efficacy and long-term outcome. Indian Heart Journal 2018;17:S384-S388

Ablation in coronary cusps - Aware of relationship to coronaries

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Supravalvar RVOT VT

  • Most from close to pulmonary valve
  • Can be above the pulmonary valve level (1)

Timmermans C, Rodriguez LM, Crijns HJ, Moorman AF, Wellens HJ. Idiopathic left bundle-branch block-shaped ventricular tachycardia may originate above the pulmonary valve. Circulation 2003; 108: 1960–1967.

Most PA-VAs missed (thought as RVOT)

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Liu … Lerman. Ubiquitous Myocardial Extensions Into the Pulmonary Artery Demonstrated by Integrated Intracardiac Echocardiography and Electroanatomic Mapping. Circ Arrhythmia 2014;7:691-700.

Pulmonary sinus cusp VT

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Liao Z, Zhan X, Wu S, Xue Y, Fang X, Liao H, et al. Idiopathic ventricular arrhythmias originating from the pulmonary sinus cusp: Prevalence, electrocardiographic/electrophysiological characteristics, and catheter ablation. J Am Coll Cardiol 2015; 66: 2633–2644.

Suspect when unsuccessful in high RVOT

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Summary

  • Complex anatomy of the outflow tracts
  • Differentiation between LVOT / RVOT
    • ECG - Precordial transition, R in V1/V2
    • EP - Activation in distal CS, signals in RVOT
  • Awareness of OT VAs from above the valve