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Electrocardiography. What is old is new again !

Raja Selvaraj
Cardiac Electrophysiologist
Professor of Cardiology
JIPMER

First ECGs - Waller and Jimmy - 1887

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Einthoven - 1912

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ECG today

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Digital ECGs

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Digital X-ray and the Radiology workstation

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ECG viewer

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ECG measurements

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Vectorcardiography

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VCG

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Electro-vectorcardiogram

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Hasitha T, … Selvaraj RJ. Ease and accuracy of ECG interpretation using 12-lead ECG versus a combination of 12-lead and vector ECG (electro-vectorcardiogram) by medical students: A prospective, randomised controlled study. J Electrocardiol. 2025 Jan-Feb;88:153830. doi: 10.1016/j.jelectrocard.2024.153830.

Single dipole and derived leads

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Derivation of elevated precordial leads

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Kalani K, Selvaraj R et al. A mathematical model for derivation of Elevated-Electrode-Placement Electrocardiogram (EEP-ECG) leads from a standard 12-lead electrocardiogram. J Electrocardiol. 2025 Mar-Apr;89:153880. doi: 10.1016/j.jelectrocard.2025.153880.

Ventricular repolarization - T wave alternans

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Chauhan VS, Selvaraj RJ. Utility of microvolt T-wave alternans to predict sudden cardiac death in patients with cardiomyopathy. Curr Opin Cardiol. 2007 Jan;22(1):25-32. doi: 10.1097/HCO.0b013e328011aa49.

Atrial Repolarization

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Pulath N, … Selvaraj RJ. Atrial repolarization in patients with left ventricular dysfunction. J Electrocardiol. 2026 Jan-Feb;94:154160. doi: 10.1016/j.jelectrocard.2025.154160.

Atrial Repolarization

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Pulath N, … Selvaraj RJ. Atrial repolarization in patients with left ventricular dysfunction. J Electrocardiol. 2026 Jan-Feb;94:154160. doi: 10.1016/j.jelectrocard.2025.154160.

ECG marker of synchrony - QRS duration

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Parale C., … Selvaraj R. Comparison of electrocardiographic parameters between left bundle optimized cardiac resynchronization therapy (LOT‐CRT) and left bundle branch pacing—cardiac resynchronization therapy (LBBP‐CRT) Pacing Clin Electrophysiol. 2023;46(8):840–847. doi: 10.1111/pace.14793.

QRS area

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Device recorded ECGs

  • Smartwatches
  • Hand held devices
  • On chest with phonocardiogram

Handheld device - ECG screening in neonates and infants

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ECG leads and phonocardiogram

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Faster to record

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Comparable QTc

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AI analysis of ECG

  • Rhythm analysis, AF identification
  • Age, sex, LV function
  • Future risk of AF

Summary

  • ECGs continue to be relevant more than 100 years later
  • Very information dense investigative modality
  • Potential still largely unexplored
  • Provides rich opportunity for research